The relationship between dysphagia and clinical types in Parkinson’s disease
Relação entre disfagia e tipos clínicos na doença de Parkinson
Douglas Monteiro; Maria das Graças Wanderley de Sales Coriolano; Luciana Rodrigues Belo; Otávio Gomes Lins
Abstract
Dysphagia is a common symptom in Parkinson’s disease, but the cause and mechanism are still unclear. It is known that the manifestations may be derived from dysphagia motor symptoms characteristic of Parkinson’s disease. Thus, the study aims to investigate whether the literature indicates the relationship between dysphagia and clinical types (predominant symptoms) in Parkinson’s disease and levodopa influences swallowing in these patients. The search was performed using databases: portal Bireme (Medline, Lilacs, IBECS, Scielo, Cochrane Library, among other banks portal) and the Pubmed website. There was no restriction regarding the year of publication and language. The descriptors used were: Parkinson’s disease and Parkinson’s disease or Swallow or deglutition or swallowing and dysphagia and Levodopa. 29 papers were found, of which only two were included in the eligibility criteria. But the articles selected are not a clear relationship between dysphagia and the classic symptoms of Parkinson’s disease, but the results show that point to an improvement in swallowing after levodopa in some patients or in patients with dyskinesia. More studies are needed that can clarify this issue, helping to guide therapeutic interventions more targeted and effective.
Keywords
Resumo
A disfagia é um sintoma comum na doença de Parkinson, porém a causa e o mecanismo permanecem obscuros. Sabe-se que manifestações disfágicas podem provir de sintomas motores característicos da doença de Parkinson. Sendo assim, o estudo tem como objetivo investigar se a literatura indica a relação entre disfagia e os tipos clínicos (sintomas predominantes) na doença de Parkinson, e se a Levodopa influencia na deglutição desses pacientes. A busca foi realizada utilizando as bases de dados: portal da Bireme (Medline, Lilacs, Ibecs, Scielo, Biblioteca Cochrane, entre outros bancos desse portal) e portal Pubmed. Não houve restrição quanto ao ano de publicação e idioma. Os descritores utilizados foram: Parkinson or Parkinsonism and Deglutition or Swallowing or Swallow and Dysphagia and Levodopa. Foram encontrados 29 artigos, dos quais apenas 2 foram incluídos segundo os critérios de elegibilidade. Porém os artigos selecionados não fazem uma relação clara entre a disfagia e os sintomas clássicos da doença de Parkinson, entretanto demonstram resultados que apontam para uma melhora da deglutição após levodopa em alguns pacientes ou em pacientes com discinesia. São necessários novos estudos que possam esclarecer tal pergunta, contribuindo para norteamento de intervenções terapêuticas mais específicas e eficazes.
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Referencias
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Submitted date:
23/08/2012
Accepted date:
17/01/2013
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