Quantitative analysis of swallowing in Parkinson's disease before and after riboflavin
Análise quantitativa da deglutição de parkinsonianos pré e pós-riboflavina
Carolina Castelli Silvério; Cícero Galli Coimbra; Brasília Maria Chiari; Henrique M. Lederman; Maria Inês Rebelo Gonçalves
Abstract
Purpose: to verify the quantitative changes in the swallowing dynamics in patients with Parkinson's disease submitted to treatment with riboflavin, red meat and poultry removed during one year period.
Methods: sixteen patients with Parkinson's disease participated in the study; the mean age was 67.25 years, the mean degree of disease severity was II to III, and the mean time since the diagnosis of the disease was 3.5 years. Videofluoroscopic evaluations were performed before and one year after treatment with riboflavin and diet with restriction of read meat and poultry. Analyzed were: presence of complaints related to swallowing and quantitative analyses of swallowing including computerized measurements of hyoid bone and cricoid cartilage displacement, opening of the superior esophageal sphincter and pharyngeal constriction.
Results: decrease of complaints was observed after administration of riboflavin. About the quantitative measures after riboflavin, there were a increase in the opening of the superior esophageal sphincter for all consistencies offered, an increase in the pharyngeal constriction for the thickened liquid, a reduction in the hyoid bone displacement, and an increase or a reduction in the cricoid cartilage displacement for each consistency, with significant reduction for the liquid.
Conclusion: quantitative measurements made in the movement of organs associated with swallowing showed no significant differences between pre- and post- riboflavin, and red meat and poultry removed.
Keywords
Resumo
Objetivo: verificar as mudanças quantitativas na dinâmica da deglutição em pacientes portadores da doença de Parkinson, submetidos à administração de riboflavina e restrição de carnes vermelhas e de aves, no período de um ano.
Métodos: participaram do estudo 16 pacientes com doença de Parkinson, com media de idade de 67,25 anos, media do nível de severidade da doença de II para III e com media de 3,5 anos de tempo de diagnóstico da doença. As avaliações videofluoroscópicas da deglutição foram realizadas antes e após um ano de administração de riboflavina e restrição de carne vermelha e de aves. Foram analisadas: presença de queixas relacionadas à deglutição e análise quantitativa por meio de medidas computadorizadas do deslocamento do osso hióide e da cartilagem cricóidea, abertura da transição faringoesofágica (TFE) e da constrição da faringe.
Resultados: verificou-se redução no percentual de queixas relacionadas à deglutição no momento pós-administração de riboflavina. Com relação às medidas quantitativas, observou-se no momento pós um discreto aumento na abertura da TFE para todas as consistências oferecidas, aumento da constrição da faringe para a consistência líquido engrossado, discreta redução dos valores de deslocamento do osso hióide, e tanto discreta redução como discreto aumento dos valores de deslocamento da cartilagem cricóidea dependendo da consistência alimentar, sendo redução significante para o líquido.
Conclusões: as medidas quantitativas realizadas na movimentação dos órgãos relacionados à deglutição não demonstraram diferenças significantes entre os momentos pré e pós-riboflavina e a restrição de carne vermelha e de aves.
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References
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Submitted date:
01/27/2013
Accepted date:
05/16/2013
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