Applicability of Mismatch Negativity in children and teenagers: a descriptive review
Aplicabilidade do Mismatch Negativity em crianças e adolescentes: uma revisão descritiva
Mirtes Bruckmann; Valdete Alves Valentins dos Santos Filha; Eliara Pinto Vieira Biaggio; Michele Vargas Garcia
Abstract
The Mismatch Negativity (MMN) is a cortical potential that occurs in response to an acoustic stimulus modification amid a repeated stimuli sequence, which reflects the brain capacity of discriminate the sound passively, in other words, without necessity the individual attention to the sound stimulus. The purpose of this study is to perform a descriptive revision about MMN, in order to identify its applicability in child and youth, in the last five years. The search was realized in the database Lilacs, SciELO, Medline and Pubmed using the following key words: Auditory Cortex, Electrophysiology and Auditory Evoked Potentials. Besides that, the words Mismatch and Negativity were used. In this revision, it were found 14 studies which evaluated child and/or youth presenting difficulties in speech articulation, specific language impairment, auditory processing disorder, Attention Deficit and Hyperactivity Disorder, dyslexia, autism, schizophrenia, psychosis, amusia, phenylketonuria and selective attention. It was possible to perform the descriptive revision about the application of MMN in child and youth, concluding that in the last five years there were a reasonable article production about the theme, however, in Brazil, there are a few studies. There is a variety of applications to MMN, though; in the national population, there is a need for scientific evidences to use this potential in the different age groups. It was found, as well, that the search for MMN studies in the databases could be done only using the word Mismatch and Negativity.
Keywords
Resumo
O Mismatch Negativity (MMN) é um potencial cortical que ocorre em resposta a uma mudança de um estímulo acústico em meio a uma sequência de repetidos estímulos, o que reflete a capacidade do cérebro em discriminar o som de modo passivo, ou seja, sem a necessidade de atenção do indivíduo ao estímulo sonoro. Diante disso, o objetivo deste estudo foi realizar uma revisão descritiva sobre o MMN, a fim de identificar a sua aplicabilidade em crianças e adolescentes nos últimos cinco anos. Para isso, realizou-se uma busca nas bases de dados Lilacs, SciELO, Medline e Pubmed utilizando os seguintes descritores: córtex auditivo, eletrofisiologia, potenciais evocados auditivos e as palavras Mismatch e Negativity. Nesta revisão, foram encontrados 14 estudos que avaliaram crianças e/ou adolescentes com dificuldade de articulação na fala, distúrbio específico de linguagem, transtorno do processamento auditivo, Transtorno do Déficit de Atenção e Hiperatividade (TDAH), dislexia, autismo, risco para esquizofrenia, psicose, amusia, fenilcetonúria e atenção seletiva. Foi possível, assim, realizar a revisão descritiva sobre a aplicação do MMN em crianças e adolescentes, concluindo-se que, nos últimos cinco anos, houve uma produção considerável de artigos sobre o tema, embora no Brasil a presença de estudos a esse respeito ainda seja escassa. Nesse sentido, apesar de existir uma variedade de aplicações para o MMN, no que diz respeito à população brasileira, necessita-se ainda de evidências científicas que assegurem o efeito deste potencial nas diferentes faixas etárias. Verificou-se, também, que a busca por estudos sobre MMN nas bases de dados citadas pode ser realizada apenas utilizando as palavras Mismatch e Negativity.
Palavras-chave
Referencias
1. Naatanen R, Gaillard A, Mantysalo S. Early selective attention effect on evoked potential reinterpreted. Acta Psychol. 1978;42(4):313-29.
2. Picton TW, Alain C, Otten L, Ritter W, Achim A. Mismatch Negativity: different water in the same river. Audiol Neurootol. 2000;5(3-4):111-39.
3. Duncan CC, Barry RJ, Connolly JF, Fischer c, Michie PT, Naatanen R et al. Event-related potentials in clinical research: Guidelines for eliciting, recording, and quantifying mismatch negativity, P300, and N400. Clin Neurophysiol. 2009;120(11):1883-908.
4. Romero ACL, Capellini AS, Frizzo ACF. Potencial cognitivo em crianças com transtorno do déficit de atenção com hiperatividade. Braz J Otorhinolaryngol. 2013;79(5):609-15.
5. Naatanen R, Paavilainen P, Rinne T, Alho K. The mismatch negativity (MMN) in basic research of central auditory processing: a review. Clin Neurophysiol. 2007;118(12):2544-90.
6. Santos MAR, Munhoz MSL, Peixoto MAL, Haase VG, Rodrigues JL, Resende LM. Contribuição do Mismatch Negativity na avaliação cognitiva de indivíduos portadores de esclerose múltipla. Braz J Otorhinolaryngol. 2006;72(6):800-7.
7. Brossi AB, Borba KC, Garcia CFD, Reis ACMB, Isaac ML. Verificação das respostas do mismatch negativity (MMN) em sujeitos adultos normais. Braz J Otorhinolaryngol. 2007;73(6):793-802.
8. Granados-Ramos DE, Torres-Morales P, Cervantes-Mendez HJ, Castañeda-Villa N, Romero-Esquiliano G. Mismatch Negativity (MMN) y lenguaje en niños preescolares hablantes del idioma español. Rev Chil Neuropsicol. 2013;8(1):1-5.
9. Rocha-Muniz CN, Lopes DMB, Schochat E. Mismatch negativity in children with specific language impairment and auditory processing disorder. Braz J Otorhinolaryngol. 2015;81(4):408-15.
10. Bishop DVM, Hardiman MJ, Barry JG. Lower-frequency event-related desynchronization: a signature of late mismatch responses to sounds, which is reduced or absent in children with specific language impairment. J Neurosci. 2011;30(46):15578-84.
11. Yang MT, Hsu CH, Yeh PW, Lee WT, Liang JS, Fu WM et al. Attention deficits revealed by passive auditory change detection for pure tones and lexical tones in ADHD children. Front Hum Neurosci. 2015;9(470):1-13.
12. Halliday LF, Barry JG, Hardiman MJ, Bishop DVM. Late, not early mismatch responses to changes in frequency are reduced or deviant in children with dyslexia: an event-related potential study. J Neurodev Disord. 2014;6(1):1-15.
13. Neuhoff N, Bruder J, Bartling J, Warnke A, Remschmidt H, Müller-Myhsok B et al. Evidence for the Late MMN as a Neurophysiological Endophenotype for Dyslexia. PLoS One. 2012;7(5):1-7.
14. Abdeltawwab MM, Baz H. Automatic Pre-Attentive Auditory Responses: MMN to Tone Burst Frequency Changes in Autistic School-Age Children. Int Adv Otol. 2015;11(1):36-41.
15. Bruggemann JM, Stockill HV, Lenroot RK, Laurens KR. Mismatch negativity (MMN) and sensory auditory processing in children aged 9-12 years presenting with putative antecedents of schizophrenia. Int J Psychophysiol. 2013;89(3):374-80.
16. Murphy JR, Rawdon C, Kelleher I, Twomey D, Markey PS, Cannon M et al. Reduced duration mismatch negativity in adolescents with psychotic symptoms: further evidence for mismatch negativity as a possible biomarker for vulnerability to psychosis. BMC Psychiatry. 2013;13(45):1-7.
17. Chobert J, François C, Velay JL, Besson M. Twelve Months of Active Musical Training in 8- to 10-Year-Old Children Enhances the Preattentive Processing of Syllabic Duration and Voice Onset Time. Cereb Cortex. 2014;24(4):956-67.
18. Goulet GM, Moreau P, Robitaille N, Peretz I. Congenital Amusia Persists in the Developing Brain after Daily Music Listening. PLoS One. 2012;7(5):1-9.
19. Sonneville LMJ, Huijbregts SC, Licht R, Sergeant JA, van Spronsen FJ. Pre-attentive processing in children with early and continuously-treated PKU. Effects of concurrent Phe level and lifetime dietary control. J Inherit Metab Dis. 2011;34(4):953-62.
20. Sussman ES. Attention matters: pitch vs. pattern processing in adolescence. Front Psychol. 2013;4(333):1-8.
Submitted date:
30/12/2015
Accepted date:
15/04/2016
Facebook
Twitter
LinkedIn
Mendeley
Email