Quality of life analysis in laryngeal cancer patients at a referral hospital in Southeastern Brazil
Análise da qualidade de vida dos pacientes com câncer de laringe em hospital de referência na região Sudeste do Brasil
Cristina Tostes Vieira Maciel; Isabel Cristina Gonçalves Leite; Romário Coelho Soares; Renata Jacob Daniel Salomão Campos
Abstract
Purpose: to estimate the quality of life and associated factors in a sample of patients with laryngeal tumor, in Southeastern Brazil.
Method: sample of 60 patients treated for laryngeal cancer in two hospitals in the city of Juiz de Fora, Minas Gerais (Brazil), city and regional center of excellence for the treatment of head and neck cancers in southeastern Brazil. With the application of the questionnaire Functional Assessment Cancer Therapy-Head & Neck, data were collected and submitted to bivariate and multivariate analysis to demonstrate the involvement of variables in the quality of life of institutions of tertiary care for treatment of cancer.
Results: in bivariate analysis (p ≤ 0.20) were significant variables: gender, years of education, analysis of treatment received, speech therapy and nutrition. After multivariate analysis also demonstrated an independent association: analysis of treatment received, speech therapy and nutrition.
Conclusions: the quality of life of patients in the study can be evaluated as satisfactory, being influenced by the physical well-being and functional. The questionnaire Functional Assessment Cancer Therapy-Head & Neck, specific for head and neck, showed that economic factors, clinical and functional, demographic are also linked to quality of life of patients with laryngeal cancer. Also demonstrated was the importance of speech therapy and nutritional rehabilitation treatment gain in quality of life of patients.
Keywords
Resumo
Objetivo: estimar a qualidade de vida e fatores a ela associados de uma amostra de pacientes portadores de tumor laríngeo, na região Sudeste do Brasil.
Método: amostra constituída por 60 pacientes em tratamento para o câncer de laringe em 2 Hospitais do município de Juiz de Fora, estado de Minas Gerais (Brasil), cidade polo regional e referência para tratamento de cânceres de cabeça e pescoço na região sudeste do Brasil. Com a aplicação do questionário Functional Assessment Cancer Therapy-Head&Neck, foram coletados os dados e submetidos à análises bivariada e multivariada, para atestar a implicação das variáveis na qualidade de vida dos pacientes de instituições de atenção terciária para tratamento de câncer.
Resultados: na análise bivariada, foram significantes as variáveis: sexo; anos de escolaridade; análise do tratamento recebido; acompanhamento fonoaudiológico e nutricional. Após a análise multivariada, ainda demonstraram associação independente: análise do tratamento recebido, tratamento fonoaudiológico e nutricional.
Conclusões: a qualidade de vida dos pacientes envolvidos no estudo pode ser avaliada como satisfatória, sendo influenciada pelo bem-estar físico e funcional. O questionário Functional Assessment Cancer Therapy-Head&Neck, específico para cabeça e pescoço, mostrou que além dos fatores socioeconômicos e clínico-funcionais, os sociodemográficos também estão ligados à qualidade de vida dos portadores de câncer de laringe. Foi demonstrada também a importância do tratamento reabilitador fonoaudiológico e nutricional no ganho da qualidade de vida dos pacientes.
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Referências
1. Brasil. INCA. Câncer de Laringe. Disponível em: <http://www.inca.gov.br/conteudo_view.asp?id=332>. Acesso em: 22 jul. 2007.
2. World Health Organization. The Impact of Cancer. Disponível em: <http://www.who.int/ncd_surveillance/infobase/web/InfobasePolicymaker/reports/Rep>. Acesso em: 11 out. 2007.
3. Sartor G, Eluf-Neto J, Travier N, Filho VW, Arcuri ASA, Kowalski et al. Riscos ocupacionais para o câncer de laringe: um estudo caso-controle. Cad Saúde Pública. 2007;23:1473-81.
4. Vartanian JG, Carvalho AL, Furia CLB, Castro Júnior G, Rocha CN, Sinitcovisky IML et al. Questionários para a avaliação da qualidade de vida em pacientes com câncer de cabeça e pescoço validados no Brasil. Rev Bras Cir Cabeça Pescoço. 2007;36(2):108-15.
5. Furia CLB. Qualidade de vida em pacientes tratados de câncer de cavidade oral, faringe e laringe em São Paulo: estudo multicêntrico. [doutorado] São Paulo (SP): Universidade de São Paulo; 2006.
6. Saito K, Shiotani A. Laryngeal function after supracricoid laryngectomy. Otolaryngol Head and Neck Surg. 2009;140(4):487-92.
7. Schindler A, Fávero E, Nudo S, Albera R, Schindler O, Cavalo AL. Long-term voice and swallowing modifications after supracricoid laryngectomy: objective, subjective, and self-assessment data. Am J Otolaryngol and Medicine and Surg. 2006;27(6):378-83.
8. Dornfeld K, Simmons JR, Karnell L. Radiation doses to structures within and adjacent to the larynx are correlated with long-term diet-and speech- related quality of life. Int J radiation Oncology Biol Phys. 2007;68(3):750-7.
9. Mowry SE, LoTempio MM, Sadeghi A, Wank KH, Wank MB. Quality of life outcomes inlaryngeal and oropharyngeal câncer patients after chemoradiation. Otorinolaryngol. Head and Neck Surg. 2008;135:565-70.
10. Aarstad HJ, Aarstad AKH, Lybak S. The amount of treatment versus quality of life in patients formerly treated for head and neck squamous cell carcinoms. Eur Arch Othorhinolayngol. 2006;263(1):9-25.
11. Van Der Schoeff MP, Derks, W, Hordjk GJH, de Leeuw RJ. The effect of age on survival and quality of life in eldery head and neck cancer patients: a long-term prospective study. Eur Arch Otorhinolaryngol. 2007;264(4):415-22.
12. Donatelli-Lassing AA, Duffy SA, Fowler KE, Ronis DL, Chepeha DB, Terrell JL. The effect of neck dissection on quality of life after chemoradiation. Otolaryngol Head and neck Surg. 2008;139(4):511-8.
13. Thomas L, Jones TM, Tandon S et al. An evolution of the University of Washington Quality of life swallowing domain following oropharyngeal cancer. Eur Arch Otorhinolaryngol. 2008;265(suppl 1):S29-S37.
14. Swinak A, Van Der Brink JL, Wieringa MH et al. Surgery for recurrent laryngeal carcinoma after radiotherapy: partial laryngectomy or total laryngectomy for a better quality of life? Otolaryngol Head and Neck Surg. 2005;132(1):95-8.
15. Lotempio MM, Wang KH, Sadeghi A, Delacure MD, Juillard DF, Wang MB. Comparison of quality of life outcomes in laryngeal cancer patients following chemoradiation vs. total laryngectomy. Otolaryngol Head and Neck Surg. 2005;132(6):948-53.
16. List MA, D'Antonio LL, Cella DF, Siston A, Mumby P, Haraf D et al. The performance status scale for head and neck cancer patients and the functional assessment of cancer therapy-head and neck scale- a study of utility and validity. Cancer. 1996;77(11):2294-301.
17. Trivedi N, Swaminathan DK, Kuriakose MA et al. Comparison of quality of life in advanced laryngeal cancer patients after concurrent chemotherapy vs total laryngestomy. Otolaryngol Head and neck Surg. 2008;139:702-7.
18. Tschiesner U, Rogers SN, Harreus U, Berghaus A, Cieza A. Content comparison of quality of life quaetionaires used in head and neck cancer based on the international classification of functioning, disability and health: a systematic review. Eur Arch Otorhinolaryngol. 2008;265(6):627-37.
19. Manfro G, Dias FL, Soares JRN, Lima RA, Reis Tl. Relação entre idade, sexo, tratamento realizado e estágio da doença com a sobrevida em pacientes terminais com carcinoma epidermoide de laringe. Rev Bras Cancerol. 2006;52(1):17-24.
20. Hashibe M, Boffeta P, Zaridze D, Shangina O, Szeszenia-Dabrowska N, Mates D et al. Contribution of tobacco and alcohol to the high rates of squamous cell carcinoma of the supraglottis in central Europe. Am J Epidemiol. 2007;165(7):814-20.
21. Lazarus CL. Effects of chemoradiotherapy on voice and swallowing. Curr Opin Otolaryngol Head Neck Surg. 2009;17(3):172-8.
22. Chaukar DA, Walvekar RR, Das AK, Deshpande MS, Pai PS, Chaturvedi P et al. Quality of life in head and neck cancer survivors: a cross-sectional survey. Am. J. Otolaryngol. Head and Neck Medicine and Surg. 2009;30(3):176-80.
23. Oozner NB, Benbow J, Downs C, Kelly C, Welch A, Paleri V. The effect of comorbidity on quality of life during radiotherapy in head and neck cancer. Otolaryngol Head and Neck Surg. 2008;139(2):268-72.
24. Tschiesner U, Linseinsen E, Coenen M, Rogers S, Harreus U, Berghaus A et al. Evaluating sequelae after head and neck cancer from the patient perspective with the help of the International Classification of Functioning, Disability and health. Eur Arch Otorhinolaryngol. 2009;266(3):425-36.
Submetido em:
05/05/2011
Aceito em:
13/07/2013
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